Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer.
作者： Alan Forster , Richard Pannell , Lesley F Drynan , Matthew McCormack , Emma C Collins
DOI: 10.1016/S1535-6108(03)00106-5
关键词: Gene 、 Allele 、 Proto-Oncogenes 、 Genetics 、 Chromosome engineering 、 Myeloid-Lymphoid Leukemia Protein 、 Biology 、 Myeloid 、 Phenotype 、 Chromosomal translocation
摘要: … both reciprocal products. We describe a system by which chromosomal translocations occur de novo during mouse development and cause tumors carrying both reciprocal translocated …
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