The preparation of cyclopentadecanone and cyclopentadecanolide from Malania oleifera Chum oil
作者： Pin Liu , Xiongmin Liu , Fang Lai , Li Ma , Weiguang Li
DOI: 10.1101/622423
关键词: Ozonolysis 、 Yield (chemistry) 、 Malania 、 Acyloin condensation 、 Organic chemistry 、 Catalysis 、 Chemistry 、 Cyclopentadecanolide 、 Fatty acid 、 Alkyl
摘要: The macrocyclic musks are of central importance in the fragrance industry. preparation cyclopentadecanone and cyclopentadecanolide from Malania oleifera Chum oil were investigated. Preparation method is three steps process: first fatty acid double bonds cut off by ozonolysis; second ozonides converted into methyl esters esterification; afterwards was achieved through acyloin condensation, reduction separation with 38.5 % overall yield. coyfclopentadecanolide two step ozonolysis triglycerides {omega}-hydroxycarboxylic acids synthesized malania chum it catalytically transformed to macrocyctic lactones, a 63% yield obtained. effect different ester groups on cyclization ,{omega}-difatty alkyl ester, catalysts triglyceride
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