Chemical composition, biological properties of Anisomeles indica Kuntze essential oil
作者： Giridhara Basappa , Vadlapudi Kumar , B.K. Sarojini , D.V. Poornima , Hari Gajula
DOI: 10.1016/J.INDCROP.2015.08.041
关键词: Antioxidant 、 Food science 、 Biology 、 MTT assay 、 Aspergillus flavus 、 Anisomeles indica 、 Preservative 、 Essential oil 、 Botany 、 Aflatoxin 、 Nootkatone
摘要: Abstract Plant essential oils are mixture of bioactive compounds that useful to humankind as therapeutics and preservatives. Present report describes the determination chemical composition Anisomeles indica Kuntze leaf oil exploration its biological properties. Farnesyl acetone, nootkatone jasmatone were major components 17 constituents identified in A. by GC–MS analysis. Essential was evaluated for antioxidant, fungitoxic, anti-aflatoxigenic cytotoxic exhibited strong antioxidant potential, with IC50 value 9.86 μL/mL. Fungitoxicity activity against Aspergillus flavus isolated from cereals pulses, minimum inhibitory concentration determined 0.66 μL/mL. inhibited AFB1 production completely at 0.6 μL/mL G1 strain partially G2 strains flavus. Cytotoxicity examined four human cancer cell lines HEK-293, HepG2, A549, K562 MTT assay. proliferation all significantly stronger cytotoxicity HepG2 cells. Results confirmed functional characters inidica special merits possessing aflatoxin suppression cytotoxicity. The potential a cheaper source active ingredients food pharmaceutical industry demonstrated.
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