AAV8, 9, Rh10, Rh43 Vector Gene Transfer in the Rat Brain: Effects of Serotype, Promoter and Purification Method
作者： Ronald L Klein , Robert D Dayton , Jason B Tatom , Karen M Henderson , Phillip P Henning
关键词: Green fluorescent protein 、 Virus 、 Transduction (genetics) 、 Serotype 、 Cell culture 、 Molecular biology 、 Virology 、 Biology 、 Hepatitis B virus 、 Iodixanol 、 Plasmid
摘要: … We proceeded to compare the robust AAV8 with some newer serotypes in this study. AAV8 … tissue efficiently, to a greater extent than AAV8. , 17 There is evidence for enhancement of …
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J. Fueyo, C. Gomez-Manzano, T.-J Liu, W.K. Alfred Yung, Delivery of cell cycle genes to block astrocytoma growth. Journal of Neuro-oncology. ,vol. 51, pp. 277- 287 ,(2001) , 10.1023/A:1010661131403
Jean-Marc Taymans, Luk H. Vandenberghe, Chris Van Den Haute, Irina Thiry, Christophe M. Deroose, Luc Mortelmans, James M. Wilson, Zeger Debyser, Veerle Baekelandt, Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain. Human Gene Therapy. ,vol. 18, pp. 195- 206 ,(2007) , 10.1089/HUM.2006.178
R KLEIN, R DAYTON, W LIN, D DICKSON, Tau gene transfer, but not alpha-synuclein, induces both progressive dopamine neuron degeneration and rotational behavior in the rat. Neurobiology of Disease. ,vol. 20, pp. 64- 73 ,(2005) , 10.1016/J.NBD.2005.02.001
Sharon Reimsnider, Fredric P Manfredsson, Nicholas Muzyczka, Ronald J Mandel, Time course of transgene expression after intrastriatal pseudotyped rAAV2/1, rAAV2/2, rAAV2/5, and rAAV2/8 transduction in the rat. Molecular Therapy. ,vol. 15, pp. 1504- 1511 ,(2007) , 10.1038/SJ.MT.6300227
Ronald L. Klein, Robert D. Dayton, Nancy J. Leidenheimer, Karen Jansen, Todd E. Golde, Richard M. Zweig, Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent Proteins Molecular Therapy. ,vol. 13, pp. 517- 527 ,(2006) , 10.1016/J.YMTHE.2005.10.008
Alyson L. Peel, Ronald L. Klein, Adeno-associated virus vectors: activity and applications in the CNS Journal of Neuroscience Methods. ,vol. 98, pp. 95- 104 ,(2000) , 10.1016/S0165-0270(00)00183-7
Cassia N. Cearley, John H. Wolfe, Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain Molecular Therapy. ,vol. 13, pp. 528- 537 ,(2006) , 10.1016/J.YMTHE.2005.11.015
Corinna Burger, Oleg S Gorbatyuk, Margaret J Velardo, Carmen S Peden, Philip Williams, Sergei Zolotukhin, Paul J Reier, Ronald J Mandel, Nicholas Muzyczka, None, Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous system. Molecular Therapy. ,vol. 10, pp. 302- 317 ,(2004) , 10.1016/J.YMTHE.2004.05.024
Thomas C. Harding, Peter J. Dickinson, Byron N. Roberts, Satya Yendluri, Melissa Gonzalez-Edick, Richard A. Lecouteur, Karin U. Jooss, Enhanced Gene Transfer Efficiency in the Murine Striatum and an Orthotopic Glioblastoma Tumor Model, Using AAV-7- and AAV-8-Pseudotyped Vectors Human Gene Therapy. ,vol. 17, pp. 807- 820 ,(2006) , 10.1089/HUM.2006.17.807
Joseph Zabner, Todd A. Derksen, Jason A. Heth, Abdi Ghodsi, Colleen S. Stein, Beverly L. Davidson, Inês Martins, Robert M. Kotin, John A. Chiorini, Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 3428- 3432 ,(2000) , 10.1073/PNAS.050581197