作者: Wei-Tao Wu , Nadine Aubry , Mehrdad Massoudi , James F. Antaki
DOI: 10.1016/J.IJENGSCI.2017.05.002
关键词: Platelet 、 Biophysics 、 Thrombus 、 Blood flow 、 Mixture theory 、 Chemistry
摘要: Abstract The near-wall enrichment of platelets strongly influences thrombus formation in vivo and vitro . This paper develops a multi-constituent continuum approach to study this phenomenon. A mixture theory model is used describe the motion plasma red blood cells (RBCs) interactions between two components. transport developed influence RBCs field on platelets. flow rectangular micro-channel, sudden expansion channel containing micro crevices (representing practical problem encountered most blood-wetted devices). simulations show that concentration near walls about five times higher than centerline. It also noticed with crevices, large number accumulate deep part may serve as nidus for excessive occurring medical devices.