A Case of Combined Sarcoidosis and Usual Interstitial Pneumonia

作者: Kazunobu Tachibana , Toru Arai , Tomoko Kagawa , Shojiro Minomo , Masanori Akira

DOI: 10.2169/INTERNALMEDICINE.51.7394

关键词: SarcoidosisLungUsual interstitial pneumoniaHoneycombingPathologyExacerbationMedicineAutopsyDiffuse alveolar damageEtiology

摘要: Sarcoidosis is a systemic granulomatous disease of unknown etiology with characteristic pulmonary lesions, which are often distributed in the upper lung fields. We describe unique case sarcoidosis lower field-dominant reticular shadows. Three years after diagnosis based on histologic findings mediastinal lymph nodes and transbronchial biopsy specimens, patient developed acute respiratory failure died. The autopsy showed usual interstitial pneumonia (UIP), honeycombing superimposed diffuse alveolar damage lungs. suggest that had both UIP, UIP later progressed to exacerbation.

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