Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10.
作者： Cristina I. Caescu , Grace R. Jeschke , Benjamin E. Turk
DOI: 10.1042/BJ20090549
关键词: Peptide library 、 Active site 、 Protease 、 Matrix metalloproteinase 、 Biology 、 Biochemistry 、 Peptide 、 Proteases 、 Enzyme 、 ADAM17 Protein
摘要: … At this position, TACE is selective for smaller aliphatic residues, whereas ADAM10 can … and protein substrates. Our results suggest that substrate selectivity of TACE and ADAM10 can …
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