Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer.
作者： Cecily P. Vaughn , Scott D. ZoBell , Larissa V. Furtado , Christine L. Baker , Wade S. Samowitz
DOI: 10.1002/GCC.20854
关键词: DNA Mutational Analysis 、 Mutant 、 Mutation 、 Biology 、 KRAS 、 Gene 、 Wild type 、 Neuroblastoma RAS viral oncogene homolog 、 Genetics 、 Colorectal cancer
摘要: … a role in treatment resistance, we sought to establish the frequency of these mutations. We evaluated 2121 colorectal tumors for mutations in codons 12 and 13 of the KRAS gene. A …
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