Augmentation of mitochondrial oxidative metabolish in lung tissue during recovery of animals from acute ozone exposure

作者: Mohammad G. Mustafa

DOI: 10.1016/0003-9861(74)90279-3

关键词: EndocrinologyRespiratory systemBiologyOrganoidMetabolismLung injuryMitochondrionInternal medicineLungBiochemistryOxidative phosphorylationPopulationBiophysicsMolecular biology

摘要: Abstract After O 3 -mediated lung injury in rats (3 ppm exposure for 4 hr) recovery was studied terms of alteration mitochondrial oxidative metabolism. As judged from 2 consumption, succinate oxidation homogenate exhibited a 20% ( P /min/lung) within 12 hr and the peak rate (55% over control, consumption observed exposed rat lungs, therefore, would be attributable primarily to increase population mitochondria. Enhanced metabolism might serve as an index assessing repair process injured lung.

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