The emerging role of lncRNAs in cancer

作者: Maite Huarte

DOI: 10.1038/NM.3981

关键词: Identification (biology)GeneticsComputational biologyGenomic StabilityRegulation of gene expressionCancerBiologyMalignant transformationTranscriptomeCellular homeostasisNeoplasms diagnosis

摘要: … to a growing number of cancer transcriptomes has indeed revealed thousands of lncRNAs whose aberrant expression is associated with different cancer types. Among the few that have …

参考文章(129)
Hadas Hezroni, David Koppstein, Matthew G. Schwartz, Alexandra Avrutin, David P. Bartel, Igor Ulitsky, Principles of long noncoding RNA evolution derived from direct comparison of transcriptomes in 17 species. Cell Reports. ,vol. 11, pp. 1110- 1122 ,(2015) , 10.1016/J.CELREP.2015.04.023
Jonathan R. Hart, Thomas C. Roberts, Marc S. Weinberg, Kevin V. Morris, Peter K. Vogt, MYC regulates the non-coding transcriptome Oncotarget. ,vol. 5, pp. 12543- 12554 ,(2014) , 10.18632/ONCOTARGET.3033
Chao Yang, Ran Tang, Xiang Ma, Younan Wang, Dakui Luo, Zekuan Xu, Yi Zhu, Li Yang, Tag SNPs in long non-coding RNA H19 contribute to susceptibility to gastric cancer in the Chinese Han population Oncotarget. ,vol. 6, pp. 15311- 15320 ,(2015) , 10.18632/ONCOTARGET.3840
John R. Prensner, Anirban Sahu, Matthew K. Iyer, Rohit Malik, Benjamin Chandler, Irfan A. Asangani, Anton Poliakov, Ismael A. Vergara, Mohammed Alshalalfa, Robert B. Jenkins, Elai Davicioni, Felix Y. Feng, Arul M. Chinnaiyan, The IncRNAs PCGEM1 and PRNCR1 are not implicated in castration resistant prostate cancer. Oncotarget. ,vol. 5, pp. 1434- 1438 ,(2014) , 10.18632/ONCOTARGET.1846
Er-bao Zhang, Rong Kong, Dan-dan Yin, Liang-hui You, Ming Sun, Liang Han, Tong-peng Xu, Rui Xia, Jin-song Yang, Wei De, Jin fei Chen, Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a. Oncotarget. ,vol. 5, pp. 2276- 2292 ,(2014) , 10.18632/ONCOTARGET.1902
Yolanda Sánchez, Maite Huarte, Long non-coding RNAs: challenges for diagnosis and therapies. Nucleic Acid Therapeutics. ,vol. 23, pp. 15- 20 ,(2013) , 10.1089/NAT.2012.0414
Je-Hyun Yoon, Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Jennifer L. Martindale, Supriyo De, Maite Huarte, Ming Zhan, Kevin G. Becker, Myriam Gorospe, LincRNA-p21 Suppresses Target mRNA Translation Molecular Cell. ,vol. 47, pp. 648- 655 ,(2012) , 10.1016/J.MOLCEL.2012.06.027
E-b Zhang, D-d Yin, M Sun, R Kong, X-h Liu, L-h You, L Han, R Xia, K-m Wang, J-s Yang, W De, Y-q Shu, Z-x Wang, P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression Cell Death and Disease. ,vol. 5, ,(2014) , 10.1038/CDDIS.2014.201
Laura Poliseno, Leonardo Salmena, Jiangwen Zhang, Brett Carver, William J. Haveman, Pier Paolo Pandolfi, A coding-independent function of gene and pseudogene mRNAs regulates tumour biology Nature. ,vol. 465, pp. 1033- 1038 ,(2010) , 10.1038/NATURE09144
Jason A West, Christopher P Davis, Hongjae Sunwoo, Matthew D Simon, Ruslan I Sadreyev, Peggy I Wang, Michael Y Tolstorukov, Robert E Kingston, The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites Molecular Cell. ,vol. 55, pp. 791- 802 ,(2014) , 10.1016/J.MOLCEL.2014.07.012