Epidemiology of tick-borne encephalitis (TBE) in Europe and its prevention by available vaccines

摘要: Tick-borne Encephalitis (TBE), which is caused by a Flavivirus, the most common tick-transmitted disease in Central and Eastern Europe Russia. Today, TBE endemic 27 European countries, has become an international public health problem. The epidemiology of changing owing to various factors, such as improvements diagnosis case reporting, increased recreational activities areas populated ticks, changes climatic conditions affecting tick habitats. Vaccination remains effective protective measure against for people living risk zones, occupationally exposed subjects travelers areas. vaccines currently use are FSME-Immun®, Encepur®, EnceVir® vaccine Moscow®. numerous studies performed on efficacy safety these have shown high level immunogenicity excellent profile. Several also cross-protection among strains belonging different subtypes.   In present paper we attempted describe continuously States overview clinical development available paying particular attention elicited vaccines.