R0 resection in the treatment of gastric cancer: Room for improvement

作者: Alberto Biondi , Roberto Persiani , Ferdinando Cananzi , Marco Zoccali , Vincenzo Vigorita

DOI: 10.3748/WJG.V16.I27.3358

关键词: Internal medicineLymph node metastasisAdjuvant therapyLymphatic metastasisMedicineR0 resectionOncologyPathological stagingSurgeryCancerQuality of lifeIn patientGastroenterologyGeneral Medicine

摘要: Gastric carcinoma is one of the most frequent malignancies in world and its clinical behavior especially depends on metastatic potential tumor. In particular, lymphatic metastasis main predictors tumor recurrence survival, current pathological staging systems reflect concept that spread relevant prognostic factor patients undergoing curative resection. This compounded by observation two-thirds gastric cancer Western presents at an advanced stage, with lymph node diagnosis. All therapeutic efforts are directed toward individualization protocols, tailoring extent resection administration preoperative postoperative treatment. The goals all these strategies to improve prognosis towards achievement a (R0 resection) minimal morbidity mortality, better quality life.

参考文章(167)
I. S. Ganpathi, J. B.-Y. So, K.-Y. Ho, Endoscopic ultrasonography for gastric cancer: does it influence treatment? Surgical Endoscopy and Other Interventional Techniques. ,vol. 20, pp. 559- 562 ,(2006) , 10.1007/S00464-005-0309-0
Ali Serdar Isguder, Okay Nazli, Ali Dogan Bozdag, Tugrul Tansug, Mehmet Ali Önal, Total gastrectomy for gastric carcinoma. Hepato-gastroenterology. ,vol. 52, pp. 302- 304 ,(2005)
Burkhard HA von Rahden, Hubert J Stein, J Rüdiger Siewert, Surgical management of esophagogastric junction tumors World Journal of Gastroenterology. ,vol. 12, pp. 6608- 6613 ,(2006) , 10.3748/WJG.V12.I41.6608
Gennaro Mancino, Federico Bozzetti, Angelo Schicchi, Marcello Schiavo, Pasquale Spinelli, Salvatore Andreola, Preoperative endoscopic ultrasonography in patients with gastric cancer. Tumori. ,vol. 86, pp. 139- 141 ,(2000) , 10.1177/030089160008600206
Chew-Wun Wu, Mao-Chih Hsieh, Su-Shun Lo, Shyh-Haw Tsay, Anna F.-Y. Li, Wing-Yiu Lui, Fang-Ku P'Eng, Prognostic Indicators for Survival After Curative Resection for Patients with Carcinoma of the Stomach Digestive Diseases and Sciences. ,vol. 42, pp. 1265- 1269 ,(1997) , 10.1023/A:1018814426278
G. Radaelli, L. Gianotti, V. Di Carlo, W. Zuliani, M. Molinari, M. Braga, M. Cristallo, L. Foppa, Surgical treatment of gastric adenocarcinoma: impact on survival and quality of life. A prospective ten year study Hepato-gastroenterology. ,vol. 43, pp. 187- 193 ,(1996)
J. R. Siewert, K. Böttcher, J. D. Roder, R. Busch, P. Hermanek, H. J. Meyer, , Prognostic relevance of systematic lymph node dissection in gastric carcinoma. German Gastric Carcinoma Study Group. British Journal of Surgery. ,vol. 80, pp. 1015- 1018 ,(1993) , 10.1002/BJS.1800800829