Expression of putative markers of pluripotency in equine embryonic and adult tissues.
作者： Cristina L. Esteves , Ruchi Sharma , Lucy Dawson , Sarah E. Taylor , Gemma Pearson
DOI: 10.1016/J.TVJL.2014.08.026
关键词: Adipose tissue 、 Homeobox protein NANOG 、 Embryonic stem cell 、 Molecular biology 、 Induced pluripotent stem cell 、 Embryo 、 SOX2 、 Mesenchymal stem cell 、 Biology 、 Rex1
摘要: Expression of several putative markers pluripotency (OCT4, SOX2, NANOG, LIN28A, REX1, DNMT3B and TERT) was examined in a range equine tissues, including early embryos, induced pluripotent stem cells (iPSCs), testis, adipose- bone marrow-derived mesenchymal stromal (MSCs), keratinocytes. Transcript levels all were highest embryos iPSCs and, except for very low or undetectable Mean expression lower testis than DNMT3B, higher MSCs. OCT4, NANOG but not the other markers, detected Of analysed, only REX1 TERT associated exclusively with horse.
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