ABCC5 and ABCG1 polymorphisms predict irinotecan-induced severe toxicity in metastatic colorectal cancer patients.
作者： Sylvia Chen , Lyne Villeneuve , Derek Jonker , Félix Couture , Isabelle Laverdière
DOI: 10.1097/FPC.0000000000000168
关键词: ABCG1 、 Oncology 、 Quality of life 、 Bioinformatics 、 ABCC5 、 Irinotecan 、 Medicine 、 Diarrhea 、 Severe toxicity 、 Internal medicine 、 Drug 、 Colorectal cancer
摘要: … Pharmacogenomic tailoring of irinotecanbased chemotherapy has been the subject of … to discover toxicity-associated markers in seven transporter genes participating in irinotecan …
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