Somatic Mutations in Breast Cancer Genomes : Discovery and Validation of Breast Cancer Genes
作者： Xiang Jiao
DOI:
关键词: Genetics 、 Bioinformatics 、 Cancer 、 Biology 、 Breast cancer 、 Genome 、 Somatic cell 、 Gene 、 Novel gene
摘要: Breast cancer is the most common in women worldwide. However, genetic alterations that lead to breast are not fully understood. This thesis aims identify novel genes of potenti ...
参考文章(197)
Robert W Carlson, Susan J Moench, M Elizabeth H Hammond, Edith A Perez, Harold J Burstein, D Craig Allred, Charles L Vogel, Lori J Goldstein, George Somlo, William J Gradishar, Clifford A Hudis, Mohammad Jahanzeb, Azadeh Stark, Antonio C Wolff, Michael F Press, Eric P Winer, Soonmyung Paik, Britt-Marie Ljung, None, HER2 testing in breast cancer: NCCN Task Force report and recommendations. Journal of The National Comprehensive Cancer Network. ,vol. 4, ,(2006) , 10.6004/JNCCN.2006.2003
John R. Nelson, Yuyang Christine Cai, Theresa L. Giesler, Joseph W. Farchaus, Shanmuuga T. Sundaram, Maria Ortiz-Rivera, Lou P. Hosta, Peter L. Hewitt, J. Anthony Mamone, C. Palaniappan, Carl W. Fuller, TempliPhi, ⌽29 DNA Polymerase Based Rolling Circle Amplification of Templates for DNA Sequencing BioTechniques. ,vol. 32, pp. 44- ,(2002) , 10.2144/JUN0208
Francis S Collins, Anna D Barker, Mapping the cancer genome. Pinpointing the genes involved in cancer will help chart a new course across the complex landscape of human malignancies. Scientific American. ,vol. 296, pp. 50- ,(2007)
Peter A. Jones, Stephen B. Baylin, The fundamental role of epigenetic events in cancer Nature Reviews Genetics. ,vol. 3, pp. 415- 428 ,(2002) , 10.1038/NRG816
Alfons Meindl, Nina Ditsch, Karin Kast, Kerstin Rhiem, Rita K. Schmutzler, Hereditary breast and ovarian cancer: new genes, new treatments, new concepts. Deutsches Arzteblatt International. ,vol. 108, pp. 323- 330 ,(2011) , 10.3238/ARZTEBL.2011.0323
Albert S. Baldwin, Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer Immunological Reviews. ,vol. 246, pp. 327- 345 ,(2012) , 10.1111/J.1600-065X.2012.01095.X
Simona Negrini, Vassilis G. Gorgoulis, Thanos D. Halazonetis, Genomic instability — an evolving hallmark of cancer Nature Reviews Molecular Cell Biology. ,vol. 11, pp. 220- 228 ,(2010) , 10.1038/NRM2858
Barry Iacopetta, Jacqueline Gayet, Xiao-Ping Zhou, Gilles Thomas, Richard Hamelin, Alex Duval, Frequent Frameshift Mutations of the TCF-4 Gene in Colorectal Cancers with Microsatellite Instability Cancer Research. ,vol. 59, pp. 4213- 4215 ,(1999)
John M. Kyriakis, Srikanth Jammulapati, Sean V. Tavtigian, Michelle Baumgard, Paul Bartel, Joseph Avruch, Arnold Oliphant, David Frank, Alexander K C Wong, Mark H. Skolnick, Thaylon Davis, Brad Swedlund, Teresa Janecki, William L. Perry, Ralph Pero, Cheryl Frye, David H F Teng, Alun Thomas, Rong Hu, Marianne Schroeder, Russell Bell, Amber Leavitt, Jeffrey T. Mitchell, David Sexton, Thomas Hattier, Pi Hsia Su, Simin Berry, James K. Hogan, Human Mitogen-activated Protein Kinase Kinase 4 as a Candidate Tumor Suppressor Cancer Research. ,vol. 57, pp. 4177- 4182 ,(1997)
Solveig Gretarsdottir, Jorunn E. Eyfjörd, Rut Valgardsdottir, Margret Steinarsdottir, Sigfridur Gudlaugsdottir, Steinunn Thorlacius, Kesara Anamthawat-Jonsson, Stefan Sigurdsson, Jon Gunnlaugur Jonasson, BRCA2 and p53 mutations in primary breast cancer in relation to genetic instability Cancer Research. ,vol. 58, pp. 859- 862 ,(1998)