Congenital mesoblastic nephroma in a young basset hound dog.

作者: S. Soldati , E. Radaelli , A. Mazzuti , E. Scanziani

DOI: 10.1111/J.1748-5827.2012.01289.X

关键词: NephrectomyAnatomyBasset HoundStromaVimentinSmooth muscleAbdominal ultrasonographyMedicineCongenital Mesoblastic NephromaLeft kidneyPathology

摘要: An 18-month-old male basset hound was presented with vomiting, diarrhoea and depression. Abdominal ultrasonography revealed a mass in the left kidney. ultrasound-guided core-biopsy indicated aggregates of spindle cells, but did not allow definitive diagnosis. Nephrectomy performed after period six months, when ultrasound examination slight increase dimensions. Histologically composed neoplastic cells forming interlacing fascicles, bundles whorls, within loose myxoid to dense collagenous stroma. Immunohistochemically were positive for vimentin smooth muscle actin. Based on these findings tumour diagnosed as congenital mesoblastic nephroma, classical variant. After two-and-a-half-year follow-up dog clinically healthy, indicating benign behaviour. To authors' knowledge, this report describes first case canine nephroma successfully treated surgically, reasonable postsurgical follow-up.

参考文章(13)
Martin Brauer, Brigitte Stöver, Michael Guschmann, Petra Degenhardt, Joachim W. Dudenhausen, Ilka B. Fuchs, Wolfgang Henrich, Prenatal diagnosis of congenital mesoblastic nephroma in 2 siblings. Journal of Ultrasound in Medicine. ,vol. 22, pp. 823- 827 ,(2003) , 10.7863/JUM.2003.22.8.823
Lei Shao, D. Ashley Hill, Elizabeth J. Perlman, Expression of WT-1, Bcl-2, and CD34 by Primary Renal Spindle Cell Tumors in Children: Pediatric and Developmental Pathology. ,vol. 7, pp. 577- 582 ,(2004) , 10.1007/S10024-004-4037-6
Rhoikos Furtwaengler, Harald Reinhard, Ivo Leuschner, Jens P. Schenk, Ulrich Goebel, Alexander Claviez, Andreas Kulozik, Andreas Zoubek, Dietrich von Schweinitz, Norbert Graf, , Mesoblastic nephroma--a report from the Gesellschaft fur Pädiatrische Onkologie und Hämatologie (GPOH). Cancer. ,vol. 106, pp. 2275- 2283 ,(2006) , 10.1002/CNCR.21836
Hashim Uddin Ahmed, Manit Arya, Gill Levitt, Patrick G Duffy, Neil J Sebire, Imran Mushtaq, Part II: Treatment of primary malignant non-Wilms' renal tumours in children Lancet Oncology. ,vol. 8, pp. 842- 848 ,(2007) , 10.1016/S1470-2045(07)70276-0
Yui SUZUKI, Katsumi TAKABA, Itaru YAMAGUCHI, Kensuke MYOUJOU, Naoya KIMOTO, Hisashi IKEGAMI, Koji SAEKI, Minami IMAIZUMI, Chie TAKADA, Histopathological, immunohistochemical and ultrastructural studies of a renal mesenchymal tumor in a young beagle dog. Journal of Veterinary Medical Science. ,vol. 74, pp. 89- 92 ,(2012) , 10.1292/JVMS.10-0504
Gabriella Sfiligoi, Gabriella Sfiligoi, Jeffrey N. Bryan, Scott A. Rizzo, Scott A. Rizzo, Carolyn J. Henry, Steven J. Steinberg, Tarraca Jackson, Tarraca Jackson, Annette N. Smith, Jeff W. Tyler, Susan E. Turnquist, Julius M. Liptak, Julius M. Liptak, Primary renal neoplasia of dogs. Journal of Veterinary Internal Medicine. ,vol. 20, pp. 1155- 1160 ,(2006) , 10.1892/0891-6640(2006)20[1155:PRNOD]2.0.CO;2
Neil J Sebire, Gordan M Vujanic, Paediatric renal tumours: recent developments, new entities and pathological features Histopathology. ,vol. 54, pp. 516- 528 ,(2009) , 10.1111/J.1365-2559.2008.03110.X
T. Takeda, T. Makita, N. Nakamura, H. Horie, Congenital mesoblastic nephroma in a dog: a benign variant of nephroblastoma. Veterinary Pathology. ,vol. 26, pp. 281- 282 ,(1989) , 10.1177/030098588902600316
Rodney L. Robison, Paul A. Grosenstein, Gregory J. Argentieri, Mixed Mesenchymal Tumor in the Kidney of a Young Beagle Dog Toxicologic Pathology. ,vol. 25, pp. 326- 328 ,(1997) , 10.1177/019262339702500311
Hashim Uddin Ahmed, Manit Arya, Gill Levitt, Patrick G Duffy, Imran Mushtaq, Neil J Sebire, Part I: Primary malignant non-Wilms' renal tumours in children Lancet Oncology. ,vol. 8, pp. 730- 737 ,(2007) , 10.1016/S1470-2045(07)70241-3