KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling

作者: Kenneth B. Schou , Johanne B. Mogensen , Stine K. Morthorst , Brian S. Nielsen , Aiste Aleliunaite

DOI: 10.1038/NCOMMS14177

关键词: Ciliary membraneLipid microdomainBiologyCiliary baseCiliogenesisCiliary transition zoneSonic hedgehogSmoothenedMotor proteinCell biology

摘要: … Here we identify kinesin-3 motor protein KIF13B as a novel member of the RPGRIP1N-C2 … KIF13B localizes to centrosomes and primary cilia in mammalian cells and we identify KIF13B …

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