Body radiation exposure in breast cancer radiotherapy: impact of breast IMRT and virtual wedge compensation techniques.

摘要: Purpose: Recent reports demonstrate a dramatically increased rate of secondary leukemia for breast cancer patients receiving adjuvant high-dose anthracycline and radiotherapy, that radiation is an independent factor the development leukemia. This study aimed to evaluate body exposure during radiotherapy characterize factors associated with exposure. Patients Methods: In prospective cohort 120 women, measurements were taken from four sites on at time radiotherapy. Multiple regression analysis was performed analyze patient treatment amount scattered radiation. Results: For standard 50 Gy minimal dose received by abdominal organs average 0.45 Gy, ranging 0.06 1.55 Gy. The use physical wedges as compensation technique most significant ( p Conclusions: patient's consistent reported be excess accordance As Low Reasonably Achievable (ALARA) principle, we recommend using IMRT or virtual wedging chemotherapy.