Diurnal variations in axial length, choroidal thickness, intraocular pressure, and ocular biometrics.

作者: Ranjay Chakraborty , Scott A. Read , Michael J. Collins

DOI: 10.1167/IOVS.11-7364

关键词: Intraocular pressureCircadian rhythmVitreous chamberAxial lengthOcular biometricsNegative associationRefractive errorOphthalmologyDiurnal temperature variationMedicine

摘要: Purpose - To investigate the pattern of diurnal variations in axial length (AL), choroidal thickness, intraocular pressure (IOP), and ocular biometrics over 2 consecutive days. Methods Measurements IOP were collected for 30 young adult subjects (15 myopes, 15 emmetropes) at 10 different times Five sets measurements each day approximately 3-hour intervals, with first measurement taken ∼9 AM final PM. Results AL underwent significant variation (P < 0.0001) that was consistently observed across The longest typically second session (mean time, 12:26) shortest 21:06). mean change 0.032 ± 0.018 mm. Choroidal thickness change, 0.029 0.016 mm; P 0.001) varied antiphase to changes. Significant also found vitreous chamber depth (VCD; 0.06 3.54 0.84 mm Hg; 0.0001). A positive association between (r2 = 0.17, VCD 0.31, a negative 0.13, There no differences magnitude timing associated refractive error. Conclusions AL, days testing.

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