An effective bioremediation approach for enhanced microbial degradation of the veterinary antibiotic sulfamethazine in an agricultural soil

摘要: The veterinary antibiotic Sulfamethazine (SMZ) contaminates soils via manure applications. Like other soil contaminants (herbicides, fungicides, and nematicides), it has to be degraded. main challenge is that SMZ biodegradation with bacteria impeded, since a bacteriostatic antibiotic, designed block microbes in their growth. In this study, we enriched the indigenous microbial community (including single strain Microbacterium sp. C448, adapted degradation) from Canadian present suitable approach, for remediation by inoculating German established on carrier particles, at environmentally relevant concentrations of 1 mg kg−1. When compared isolated SMZ-degrading (also obtained Canada), outperformed mineralization rates soil. negligible native was successfully increased 44 57 % within 46 days, community. sustainability capacity proven rapid second application 14C-SMZ 112 days after first. pronounced high amount non-extractable 14C-residues (NER) inoculated indicate NER are mainly biogenic origin (metabolically fixed 14C). Therefore, applied inoculation approach decreased risk persistent residues. Together our former studies, specific tested three substances different physico-chemical properties, indicating bioremediation technique might also used substances.