Symptomatic portal biliopathy: a single centre experience from the UK.

摘要: Background and methods Biliary obstruction as a consequence of portal biliopathy, because extrahepatic vein occlusion is an uncommon cause biliary disease in the western world. We reviewed all patients presenting to Regional Liver Transplant Unit Birmingham, UK with symptomatic biliopathy between 1992 2005 report presentation, investigation, management outcome these complex patients. Results Thirteen were followed up for median 2 years (range 1-18 years). Jaundice was feature cases associated bile duct stones or debris 77% (10 13) cases. Successful treatment problems achieved by decompression six (metallic stent=three, plastic stent=one, combined procedure=one sphincterectomy=one) three (transjugular intrahepatic portosystemic shunt = two, meso-caval one). drainage could not be endoscopically one case that accepted liver small bowel transplantation. Three had spontaneous resolution without recurrence over follow-up period. Ten (77%) experienced gastrointestinal bleeding. Two deaths period occurred; both hypertensive Conclusion Endoscopic (sphincterectomy stone extraction stent insertion) effective initial therapy biliopathy. In persistent porto-systemic shunting surgical) should considered, however, extent vascular thrombosis precludes this most