RGG motif proteins: Modulators of mRNA functional states

作者: Purusharth Rajyaguru , Roy Parker

DOI: 10.4161/CC.20716

关键词: Translation (biology)Rotavirus translationGeneticsInitiation factorEIF4GCell biologyEukaryotic initiation factorEIF4EEukaryotic translation initiation factor 4 gammaFive prime untranslated regionBiology

摘要: A recent report1 demonstrates that a subset of RGG-motif proteins can bind translation initiation factor eIF4G and repress mRNA translation. This adds to the growing number roles play in modulating transcription, splicing, export now Herein, we review nature breadth functions proteins. In addition, interaction some other repressors with highlights role as general modulator function not solely factor.

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