Tetrandrine suppresses lipopolysaccharide-induced microglial activation by inhibiting NF-κB and ERK signaling pathways in BV2 cells.

作者: Yalong Dang , Yongsheng Xu , Wentao Wu , Weiyi Li , Yanran Sun

DOI: 10.1371/JOURNAL.PONE.0102522

关键词: Signal transductionViability assayTetrandrineCell signalingBiologyNF-κBApoptosisNFKB1Molecular biologyTumor necrosis factor alpha

摘要: … Next, we examined MAPK activity in BV2 cells. MAPKs comprise three major signaling molecules: extracellular signal-regulated kinase 1/2 (ERK 1/2), p38 MAPK, and c-Jun N-terminal …

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