process for the preparation of sucralose of high purity

作者: Kamlesh Shankarlal Kanzariya , Pandurang Balwant Deshpande , Sanjiv Onkarsingh Tomer , Piyush Maheshbhai Rana , Parven Kumar Luthra

DOI:

关键词: SucraloseNuclear chemistrySolventChromatographyDissolutionPhase (matter)ChemistryImpurityScientific method

摘要: The present invention relates to an improved process for the preparation of Sucralose having purity at least 99.6% comprising steps (i) dissolving substantially impure in water (ii) treating solution obtained step with a partially immiscible solvent (iii) washing said phase amount sufficient remove polar impurities (iv) crystallizing product from (v) recrystallizing solid water.

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