Histone deacetylase inhibitors as potential anti-skin cancer agents.

作者: Alison Dahler , Anthony Dicker , Nicholas Saunders , Susan Jones , Claudia Popa

DOI:

关键词: Squamous DifferentiationCancer researchSodium butyrateButyrateTrichostatin ABiologyHistone deacetylaseHistone H4Squamous carcinomaEpidermoid carcinoma

摘要: The regulation of squamous differentiation is a tightly regulated process involving transcriptional repression and activation. Previous studies have established that squamous …

参考文章(39)
L.S. Cousens, D. Gallwitz, B.M. Alberts, Different accessibilities in chromatin to histone acetylase. Journal of Biological Chemistry. ,vol. 254, pp. 1716- 1723 ,(1979) , 10.1016/S0021-9258(17)37831-6
Vincent F. Vellucci, Zhao-ling Zhou, Michael Reiss, Mutant p53 Tumor Suppressor Gene Causes Resistance to Transforming Growth Factor β1 in Murine Keratinocytes Cancer Research. ,vol. 53, pp. 899- 904 ,(1993)
M. Vettese-Dadey, P. A. Grant, T. R. Hebbes, C. Crane- Robinson, C. D. Allis, J. L. Workman, Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. The EMBO Journal. ,vol. 15, pp. 2508- 2518 ,(1996) , 10.1002/J.1460-2075.1996.TB00608.X
C. Van Lint, S. Emiliani, M. Ott, E. Verdin, Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. The EMBO Journal. ,vol. 15, pp. 1112- 1120 ,(1996) , 10.1002/J.1460-2075.1996.TB00449.X
Alison L. Dahler, Anthony J. Dicker, Nicholas A. Saunders, Susan J. Jones, E2F1 messenger RNA is destabilized in response to a growth inhibitor in normal human keratinocytes but not in a squamous carcinoma cell line Cancer Research. ,vol. 58, pp. 1646- 1649 ,(1998)
S. Dalton, Cell cycle regulation of the human cdc2 gene. The EMBO Journal. ,vol. 11, pp. 1797- 1804 ,(1992) , 10.1002/J.1460-2075.1992.TB05231.X
Alexander Brehm, Eric A. Miska, Dennis J. McCance, Juliet L. Reid, Andrew J. Bannister, Tony Kouzarides, Retinoblastoma protein recruits histone deacetylase to repress transcription Nature. ,vol. 391, pp. 597- 601 ,(1998) , 10.1038/35404
Daniel Y. Lee, Jeffrey J. Hayes, Dmitry Pruss, Alan P. Wolffe, A positive role for histone acetylation in transcription factor access to nucleosomal DNA Cell. ,vol. 72, pp. 73- 84 ,(1993) , 10.1016/0092-8674(93)90051-Q