Bioimpedance Resistance Indices and Cell Membrane Capacitance Used to Assess Disease Status and Cell Membrane Integrity in Children with Nephrotic Syndrome
作者： Steven Brantlov , Lars Jødal , René Frydensbjerg Andersen , Aksel Lange , Søren Rittig
DOI: 10.1155/2019/4274856
关键词: Disease status 、 Nephrotic syndrome 、 Clinical manifestation 、 Extracellular fluid 、 Endocrinology 、 Cell membrane 、 Medicine 、 Body water 、 Intracellular 、 Internal medicine 、 Cell integrity
摘要: Background. Accumulation of extracellular water (ECW) is a major clinical manifestation nephrotic syndrome (NS) in children. Bioimpedance spectroscopy (BIS) simple, noninvasive technique that reflects body volumes. BIS can further measure cell membrane capacitance (C ), which may be altered NS. The aims the study were to explore how measurements could reflect disease status NS, while avoiding prediction equations are often only validated adult populations. Methods. involved 8 children (2-10 years) with active NS (ANS group), 5 also studied at remission (NSR as well 38 healthy similar age (HC group). determined resistances R , and (reflecting total water, intracellular water) C . Also resistance indices based on height (H) considered, RI = H2/R. Results. It was found significantly lower ANS group than both NSR HC groups (p < 0.05). Conclusion. distinguish from well-treated Studies more warranted.
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