Patent Highlights April–May 2019

J Michael Wells, Patricia L Jackson, Liliana Viera, Surya P Bhatt, Joshua Gautney, Guy Handley, R Wilson King, Xin Xu, Amit Gaggar, William C Bailey, Mark T Dransfield, J Edwin Blalock, None, A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. ,vol. 192, pp. 934- 942 ,(2015) , 10.1164/RCCM.201503-0543OC

Zhifei Cao, Meimei Bao, Lucio Miele, Fazlul H. Sarkar, Zhiwei Wang, Quansheng Zhou, Tumour vasculogenic mimicry is associated with poor prognosis of human cancer patients: A systemic review and meta-analysis European Journal of Cancer. ,vol. 49, pp. 3914- 3923 ,(2013) , 10.1016/J.EJCA.2013.07.148

Peter K. Stys, Gerald W. Zamponi, Jan van Minnen, Jeroen J. G. Geurts, Will the real multiple sclerosis please stand up? Nature Reviews Neuroscience. ,vol. 13, pp. 507- 514 ,(2012) , 10.1038/NRN3275

Elvin Wagenblast, Mar Soto, Sara Gutiérrez-Ángel, Christina A. Hartl, Annika L. Gable, Ashley R. Maceli, Nicolas Erard, Alissa M. Williams, Sun Y. Kim, Steffen Dickopf, J. Chuck Harrell, Andrew D. Smith, Charles M. Perou, John E. Wilkinson, Gregory J. Hannon, Simon R. V. Knott, A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis Nature. ,vol. 520, pp. 358- 362 ,(2015) , 10.1038/NATURE14403

Tolga Eichhorn, Dominic Winter, Berthold Büchele, Natalie Dirdjaja, Martin Frank, Wolf-Dieter Lehmann, Rolf Mertens, R. Luise Krauth-Siegel, Thomas Simmet, Joachim Granzin, Thomas Efferth, Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum Biochemical Pharmacology. ,vol. 85, pp. 38- 45 ,(2013) , 10.1016/J.BCP.2012.10.006

Miyoung Kim, Jeehye Maeng, Kyunglim Lee, Dimerization of TCTP and its clinical implications for allergy Biochimie. ,vol. 95, pp. 659- 666 ,(2013) , 10.1016/J.BIOCHI.2012.10.007

David R. Gibb, Sheinei J. Saleem, Natalia S. Chaimowitz, Joel Mathews, Daniel H. Conrad, The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity. Molecular Immunology. ,vol. 48, pp. 1319- 1327 ,(2011) , 10.1016/J.MOLIMM.2010.12.005

Denise E. de Almeida, Song Ling, Joseph Holoshitz, New insights into the functional role of the rheumatoid arthritis shared epitope FEBS Letters. ,vol. 585, pp. 3619- 3626 ,(2011) , 10.1016/J.FEBSLET.2011.03.035

R. Engelstein, H. Ovadia, R. Gabizon, Copaxone interferes with the PrPSc–GAG interaction European Journal of Neurology. ,vol. 14, pp. 877- 884 ,(2007) , 10.1111/J.1468-1331.2007.01803.X

Charles G. Smith, Gary D. Gray, Robert G. Carlson, Arthur R. Hanze, Biochemical and biological studies with tubercidin (7-deaza-adenosine), 7-deazainosine and certain nucleotide derivatives of tubercidin Advances in Enzyme Regulation. ,vol. 5, pp. 121- 151 ,(1967) , 10.1016/0065-2571(67)90013-1