Profile of clindamycin phosphate 1.2%/benzoyl peroxide 3.75% aqueous gel for the treatment of acne vulgaris.

摘要: Acne vulgaris is a common and chronic skin disease, frequent source of morbidity for affected patients. Treatment acne often difficult due to the multifactorial nature this disease. Combination therapy, such as that containing clindamycin benzoyl peroxide, has become standard care. Several fixed formulations 1% peroxide varying concentrations are available have been used with considerable success. The major limitation irritation dryness from higher combination providing optimal efficacy tolerability yet be determined. Recently, 3.75% formulation was developed. Studies suggested may safe effective treatment regimen patients vulgaris. Here, we provide brief review pathogenesis, clindamycin, profile new Clindamycin-BP gel moderate-to-severe