Diabetes: a time for excitement-and concern. Hopeful signs exist that the ravages of diabetes can be tamed.

作者: T. Orchard

DOI: 10.1136/BMJ.317.7160.691

关键词: DemographyMedicineDiseaseGlobal healthType 2 diabetesPopulationIncidence (epidemiology)Type 1 diabetesEpidemiologyEthnic group

摘要: Editorial p 693 Papers pp 703, 713, 720 These are exciting, and exasperating, times for people interested in diabetes. On the one hand, a tremendous volume of research is underway assessing both new prevention treatment protocols; on other, incidence (and associated mortality morbidity) this disease continues to rise with little sign abating. Indeed, by 2010 world's diabetic population will probably have doubled from an estimated 110 million 1994 221 2010.1 What we learnt recently about epidemiology, causation, condition? Prevalence varies widely ethnic group country (adult rates range <2% rural Bantu Tanzania nearly 50% US Pima Indians South Pacific Naurauns1). Rates also relatively high “transplanted populations,” such as Asians Europe2 African Americans.3 The projected increase rates, however, universal. Though mainly due type 2 diabetes, alarming increases 1 been observed many studies. For example, recent report Allegheny County, USA, showed first time that diabetes adolescent Americans now exceed those whites.4 Whether relates increasing among adolescents young adults elsewhere unclear, 5 6 distinction between often …

参考文章(30)
UK Prospective Diabetes Study Group, None, Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 BMJ. ,vol. 317, pp. 703- 713 ,(1998)
Owen Oe, Cahill Gf, Starvation and survival. Transactions of the American Clinical and Climatological Association. ,vol. 79, pp. 13- 20 ,(1968)
KM Flegal, MD Carroll, RJ Kuczmarski, CL Johnson, Overweight and obesity in the United States: prevalence and trends, 1960–1994 International Journal of Obesity. ,vol. 22, pp. 39- 47 ,(1998) , 10.1038/SJ.IJO.0800541
I. M. Libman, R. E. LaPorte, D. Becker, J. S. Dorman, A. L. Drash, L. Kuller, Was There an Epidemic of Diabetes in Nonwhite Adolescents in Allegheny County, Pennsylvania? Diabetes Care. ,vol. 21, pp. 1278- 1281 ,(1998) , 10.2337/DIACARE.21.8.1278
T. Tuomi, L. C. Groop, P. Z. Zimmet, M. J. Rowley, W. Knowles, I. R. Mackay, Antibodies to Glutamic Acid Decarboxylase Reveal Latent Autoimmune Diabetes Mellitus in Adults With a Non—Insulin-Dependent Onset of Disease Diabetes. ,vol. 42, pp. 359- 362 ,(1993) , 10.2337/DIAB.42.2.359
M.S. Hammersley, L.C. Meyer, R.J. Morris, S.E. Manley, R.C. Turner, R.R. Holman, The fasting hyperglycaemia study: I. Subject identification and recruitment for a non—insulin-dependent diabetes prevention trial Metabolism-clinical and Experimental. ,vol. 46, pp. 44- 49 ,(1997) , 10.1016/S0026-0495(97)90317-6
D R McCance, D J Pettitt, R L Hanson, L T H Jacobsson, W C Knowler, P H Bennett, Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? BMJ. ,vol. 308, pp. 942- 945 ,(1994) , 10.1136/BMJ.308.6934.942