The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy.
作者： Guo Li , Yuan Tian , Wei-Guo Zhu
DOI: 10.3389/FCELL.2020.576946
关键词: Cell biology 、 Transcriptional regulation 、 Acetylation 、 Regulation of gene expression 、 Protein degradation 、 Histone Acetyltransferases 、 Biology 、 Nucleosome 、 Histone 、 Chromatin
摘要: Genetic mutations and abnormal gene regulation are key mechanisms underlying tumorigenesis. Nucleosomes, which consist of DNA wrapped around histone cores …
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