The Microbiome and Sustainable Healthcare.

摘要: Increasing prevalences, morbidity, premature mortality and medical needs associated with non-communicable diseases conditions (NCDs) have reached epidemic proportions placed a major drain on healthcare systems global economies. Added to this are the challenges presented by overuse of antibiotics increased antibiotic resistance. Solutions needed that can address NCDs increasing resistance, maximize preventative measures, balance available services economic realities. Microbiome management including microbiota seeding, feeding, rebiosis appears likely be core component path toward sustainable healthcare. Recent findings indicate that: (1) humans mostly microbial (in terms numbers cells genes); (2) immune dysfunction misregulated inflammation pivotal in majority NCDs; (3) microbiome status affects early education risk NCDs, (4) certain infections. Management reduce later-life health and/or treat emerging spare use recurrent infections may provide more effective strategy across life course particularly when personalized medicine approach is considered. This review will examine potential for contribute