Are constipation drugs effective and safe to be used in children?: a review of the literature

摘要: Introduction: Functional constipation is a common and often enduring problem in childhood. Although functional well defined by the Rome III criteria, these criteria have not always been integrated general practice. Early diagnosis treatment are key factors with respect to successful long-term outcome, as chronic has negative effect on quality of life burden for public healthcare system. The safety laxatives used paediatric-functional based well-designed trials carried out mostly adults. Therefore, we conducted review literature outlining evidence efficacy constipation. Areas covered: This clearly shows lack large placebo-controlled children any interpretation regards effectiveness or difficult extended...