Application of Silver Degeneration Stains for Neurotoxicity Testing

摘要: Silver staining procedures have been used in numerous ways to render a variety of physical and biological features visible. In tissue, histologic protocols use silver visualize diverse structures or features, such as reticulin, melanin, fungi, chromosome bands, nucleolar organizing regions, different the nervous system. A comparison specific steps these indicates that is "directed" stain any given feature by type fixation, pretreatment ("mordanting"), composition silver-containing solution(s), form development (reduction). Since mechanisms not understood historically (nor are they now), each method was developed trial error. Keystone methods those Bodian Bielschowsky exploit system's affinity for (argyrophilia). The beginning new era brain research came with recognition distinct silver-impregnated morphologic changes occurring ...