Dynamic force responses of skeletal muscle during stretch-shortening cycles.

摘要: Muscle damage due to stretch–shortening cycles (i.e., cyclic eccentric/concentric muscle actions) is one of the major concerns in sports and occupational related activities. Mechanical responses whole have been associated with neural motor units, connective tissues, force generation mechanism. The objective this study was introduce a new method quantify real-time changes skeletal forces rats during injurious cycles. Male Sprague Dawley (n=24) were selected for use study. dorsi flexor group exposed either 150 (n=12) or 15 isometric contractions vivo using dynamometer electrical stimulation. after exposure verified by non-recoverable deficit at 48 h presence myofiber necrosis. Variations dynamic analyzed decomposing signature into peak (F peak), minimum min), average mean), a). After 15th set cycles, decrease parameters, F peak, min, mean, a, 50% (P<0.0001), 26% (P=0.0055), 68% respectively. Our results showed that both induce reduction force. However, induced fully recovered break while did not. Histopathologic assessment tibialis anterior significant degeneration necrosis inflammation, muscles no necrosis, limited inflammation. suggest can be identified decrement also variations