Resection of colorectal liver metastases with extrahepatic disease.

作者: Robbert J. de Haas , Dennis A. Wicherts , René Adam

DOI: 10.1159/000184737

关键词: GastroenterologyMedicineSurvival rateHepatectomyConcomitantPeritoneal NeoplasmRadiologyInternal medicineContraindicationLymph nodeChemotherapySurvival analysis

摘要: Extrahepatic disease in combination with colorectal liver metastases has long been considered an absolute contraindication for surgery. However, many reported series, long-term survival is achieved selected patients concomitant extrahepatic as the resection of all metastatic sites complete. Owing to these results, increasing number advanced are now being referred For and lung metastases, sequential both proven be safe, offering a 5-year rate more than 30%. On contrary, hepatectomy combined regional lymph node can only provide case pedicular involvement. Furthermore, control by preoperative chemotherapy appears crucial. peritoneal carcinomatosis, aggressive treatment combining cytoreductive surgery intraperitoneal offer chance prolonged limited extension. In conclusion, intra- should if complete controlled chemotherapy. Long-term could they managed experienced multidisciplinary teams.

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