Transformation of full 4 × 4 Mueller matrices: a quantitative technique for biomedical diagnosis

摘要: Polarization images contain abundant microstructural information of samples. Recently, as a comprehensive description the structural and optical properties complex media, Mueller matrix imaging has been widely applied to biomedical studies, especially cancer detections. In previous works, we proposed technique transform backscattering 3 × matrices into group quantitative parameters with clear relationships specific microstructures. this paper, extend transformation method full 4 both back forward scattering directions. Using experimental results phantoms Monte Carlo simulation based on sphere-cylinder birefringence model, fit elements trigonometric curves in polar coordinates obtain new set parameters, which can be expressed analytical functions 16 elements. Both simulated demonstrate that have simple characteristic properties, including densities orientations fibrous structures, sizes scatterers, depolarization power We also apply human liver cancerous tissues. Preliminary show quantitatively reflect formation birefringent tissues accompanying processes. The findings presented study useful for vivo or vitro polarization diagnostic applications.