Thiazole and thiadiazole compounds for inflammation and immune-related uses
作者： Nha Huu Vo , Qinglin Che , Yu Xie , Shoujun Chen
DOI:
关键词: Thiazole 、 Inflammation 、 Prodrug 、 Immune system 、 Chemistry 、 Stereochemistry 、 Salt (chemistry)
摘要: The invention relates to compounds of structural formula (I) or a pharmaceutically acceptable salt, solvate, clathrate, prodrug thereof, wherein R'i, X, X', L and Y are defined herein. These useful as immunosuppressive agents for treating preventing inflammatory conditions, allergic disorders, immune disorders.
lens.org 参考文章(56)
Shigeru Chikase, Yukiko Yokoi, Amorphous antibiotic composition comprising cefditoren pivoxil ,(2004)
Akiko Itai, Tatsuo Nagano, Tomomi Saotome, Susumu Muto, Inhibitors against the production and release of inflammatory cytokines ,(2001)
Isao Iwataki, Takao Iwasa, Elizabeth Laura Moyano, Renpei Hatano, Insecticidal aminothiazole derivatives ,(2003)
Akiko Itai, Susumu Muto, Inhibitors against the activation of ap-1 and nfat ,(2003)
Seiji Miwatashi, Ken-ichi Naruo, Shigenori Ohkawa, Hiroyuki Kimura, Substituted 1,3-thiazole compounds, their production and use ,(2001)
Goro Miyakoda, Shinobu Sueyoshi, Kazuyoshi Kitano, Isao Takemura, Hisashi Nagamoto, Hiroshi Yamashita, Muneaki Kurimura, Takayuki Matsuzaki, Toyoki Mori, Masatoshi Chihiro, Fujio Tabusa, Agent for inhibition of cytokine production and agent for inhibition of cell adhesion ,(1997)
Jill E. Wood, Hanno Wild, John Lyons, Daniel H. Rogers, Michael E. Katz, Yolanda V. Caringal, Wendy Lee, Robert Dally, Roger A. Smith, Cheri L. Blum, Raf kinase inhibitors ,(1998)
Alejandro Zaffaroni, Bandage for administering drugs ,(1969)
Jason M. Guernon, Yong-Jin Wu, Kenneth M. Boy, 2-aryl thiazole derivatives as kcnq modulators ,(2003)
Paul W. Collins, Steven W. Kramer, Donald J. Rogier, Roland S. Rogers, Jeffery S. Carter, Thomas D. Penning, John J. Talley, Substituted thiazoles for the treatment of inflammation ,(1995)