Methods of therapeutic monitoring of phenylacetic acid prodrugs
作者： Masoud Mokhtarani , Bruce Scharschmidt
DOI:
关键词: Phenylacetic acid 、 Chromatography 、 Therapeutic monitoring 、 Chemistry 、 Prodrug
摘要: The present disclosure provides methods for adjusting the dosage of PAA prodrugs (e.g., HPN-100, PBA) based on measurement and PAGN in plasma calculating PAA:PAGN ratio so as to determine whether conversion is saturated.
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