Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells.

作者: Qing Yuan , Ramesh M. Ray , Mary Jane Viar , Leonard R. Johnson

DOI: 10.1152/AJPGI.2001.280.1.G130

关键词: Carboxy-lyasesAdenosylmethionine decarboxylaseEnzyme inhibitorOrnithine decarboxylaseBiologyPolyamineBiochemistryOrnithine decarboxylase antizymeSperminePutrescine

摘要: Ornithine decarboxylase (ODC) is feedback regulated by polyamines. ODC antizyme mediates this process forming a complex with and enhancing its degradation. It has been reported that polyamin...

参考文章(65)
J L Bueb, A Da Silva, M Mousli, Y Landry, Natural polyamines stimulate G-proteins. Biochemical Journal. ,vol. 282, pp. 545- 550 ,(1992) , 10.1042/BJ2820545
R Poulin, G Pelletier, A E Pegg, Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells. Biochemical Journal. ,vol. 311, pp. 723- 727 ,(1995) , 10.1042/BJ3110723
Y Murakami, S Matsufuji, K Tanaka, A Ichihara, S Hayashi, Involvement of the proteasome and antizyme in ornithine decarboxylase degradation by a reticulocyte lysate Biochemical Journal. ,vol. 295, pp. 305- 308 ,(1993) , 10.1042/BJ2950305
Neha Shah, Thresia Thomas, Akira Shirahata, Leonard H. Sigal, T. J. Thomas, Activation of nuclear factor kappaB by polyamines in breast cancer cells. Biochemistry. ,vol. 38, pp. 14763- 14774 ,(1999) , 10.1021/BI991291V
R. Kanamoto, T. Kameji, S. Iwashita, K. Igarashi, S. Hayashi, Spermidine-induced destabilization of ornithine decarboxylase (ODC) is mediated by accumulation of antizyme in ODC-overproducing variant cells. Journal of Biological Chemistry. ,vol. 268, pp. 9393- 9399 ,(1993) , 10.1016/S0021-9258(18)98363-8
C.S. Coleman, B.A. Stanley, R. Viswanath, A.E. Pegg, Rapid exchange of subunits of mammalian ornithine decarboxylase. Journal of Biological Chemistry. ,vol. 269, pp. 3155- 3158 ,(1994) , 10.1016/S0021-9258(17)41842-4
K Ito, K Kashiwagi, S Watanabe, T Kameji, S Hayashi, K Igarashi, Influence of the 5'-untranslated region of ornithine decarboxylase mRNA and spermidine on ornithine decarboxylase synthesis. Journal of Biological Chemistry. ,vol. 265, pp. 13036- 13041 ,(1990) , 10.1016/S0021-9258(19)38263-8
Patricia Moore, Marian E. Swendseid, Dietary Regulation of the Activities of Ornithine Decarboxylase and S-Adenosylmethionine Decarboxylase in Rats Journal of Nutrition. ,vol. 113, pp. 1927- 1935 ,(1983) , 10.1093/JN/113.10.1927
Y Murakami, S Matsufuji, Y Miyazaki, S Hayashi, Destabilization of ornithine decarboxylase by transfected antizyme gene expression in hepatoma tissue culture cells. Journal of Biological Chemistry. ,vol. 267, pp. 13138- 13141 ,(1992) , 10.1016/S0021-9258(18)42182-5