Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
作者： Gina M DeNicola , Florian A Karreth , Timothy J Humpton , Aarthi Gopinathan , Cong Wei
DOI: 10.1038/NATURE10189
关键词: Cellular detoxification 、 Biology 、 NFE2L2 、 Carcinogenesis 、 Mediator 、 Cell biology 、 Molecular biology 、 KEAP1 、 Oncogene 、 Repressor 、 Transcription factor
摘要: … Nrf2 target genes were recently identified, indicating that enhanced ROS detoxification and additional Nrf2 … Here, we investigated ROS metabolism in primary murine cells following the …
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