Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection.
作者： Jean-Sébastien Palerme , Po Ching Pan , Cameron T. Parsons , Sophia Kathariou , Todd J. Ward
关键词: Nucleotide substitution 、 Microbiology 、 Urinary system 、 Encephalitis 、 Biology 、 Multilocus genotyping 、 Virology 、 Listeria monocytogenes 、 Serotype
摘要: Listeria monocytogenes, a well-described cause of encephalitis and abortion in ruminants food-borne illness humans, is rarely associated with disease companion animals. A case urinary tract infection an atypical, weakly hemolytic L. monocytogenes strain described diabetic dog. The serotype the isolate was determined to be 1/2a (3a), multilocus genotyping pattern 2.72_1/2a. nucleotide substitution (Gly145Asp) detected at residue 145 promoter prfA region. This within critical helix-turn-helix motif PrfA. source remains unknown, dog recovered after 4-week course cephalexin (30 mg/kg orally twice daily).
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