Circulating dopamine level, in lung carcinoma patients, inhibits proliferation and cytotoxicity of CD4+ and CD8+ T cells by D1 dopamine receptors: an in vitro analysis.

作者: Baisakhi Saha , Amal Chandra Mondal , Sujit Basu , Partha Sarathi Dasgupta , None

DOI: 10.1016/S1567-5769(01)00068-6

关键词: T cellBiologyInternal medicineDopamine receptorCD8EndocrinologyDopamineLung cancerImmune systemCytotoxic T cellReceptor

摘要: … dopamine … of dopamine receptor mediated elevation of intracellular cAMP in these cell populations. The results may be of significance in understanding the role of peripheral dopamine …

参考文章(41)
R L Cohen, D A Chambers, R L Perlman, J M Cook-Mills, INHIBITION OF LYMPHOCYTE ACTIVATION BY CATECHOLAMINES : EVIDENCE FOR A NON-CLASSICAL MECHANISM OF CATECHOLAMINE ACTION Immunology. ,vol. 85, pp. 544- 549 ,(1995)
Vladimir Kolenko, Patricia Rayman, Biswajit Roy, Martha K. Cathcart, John O’Shea, Raymond Tubbs, Lisa Rybicki, Ronald Bukowski, James Finke, Downregulation of JAK3 protein levels in T lymphocytes by prostaglandin E2 and other cyclic adenosine monophosphate-elevating agents: impact on interleukin-2 receptor signaling pathway. Blood. ,vol. 93, pp. 2308- 2318 ,(1999) , 10.1182/BLOOD.V93.7.2308
Robert H. Wiltrout, Ronald M. Bukowski, Dan L. Longo, James H. Finke, John J. O'Shea, Jill Stanley, Raymond R. Tubbs, Seiji Kudoh, Eric Klein, Hiromoto Mizoguchi, Arnold H. Zea, Augusto C. Ochoa, Loss of T-Cell Receptor ζ Chain and p56lck in T-Cells Infiltrating Human Renal Cell Carcinoma Cancer Research. ,vol. 53, pp. 5613- 5616 ,(1993)
S Habu, Y Tokuda, K Okumura, Y Nakamura, A Kawasaki, M Iwasawa, T Nishimura, Y Takeuchi, Generation propagation, and targeting of human CD4+ helper/killer T cells induced by anti-CD3 monoclonal antibody plus recombinant IL-2. An efficient strategy for adoptive tumor immunotherapy. Journal of Immunology. ,vol. 148, pp. 285- 291 ,(1992)
CRISTINA MISSALE, S. RUSSEL NASH, SUSAN W. ROBINSON, MOHAMED JABER, MARC G. CARON, Dopamine Receptors: From Structure to Function Physiological Reviews. ,vol. 78, pp. 189- 225 ,(1998) , 10.1152/PHYSREV.1998.78.1.189
Chiung-Wen Tsao, Yee-Shin Lin, Juei-Tang Cheng, Effect of dopamine on immune cell proliferation in mice. Life Sciences. ,vol. 61, ,(1997) , 10.1016/S0024-3205(97)00962-4
Sujit Basu, Partha Sarathi Dasgupta, Dopamine, a neurotransmitter, influences the immune system. Journal of Neuroimmunology. ,vol. 102, pp. 113- 124 ,(2000) , 10.1016/S0165-5728(99)00176-9
Fuad Lechin, Bertha van der Dijs, Giovanna Vitelli-Florez, Scarlett Lechin-Baez, Jose Azocar, Alejandra Cabrera, Alex Lechin, Hector Jara, Marcel Lechin, Francisco Gomez, Luis Rocha, Psychoneuroendocrinological and immunological parameters in cancer patients: involvement of stress and depression. Psychoneuroendocrinology. ,vol. 15, pp. 435- 451 ,(1990) , 10.1016/0306-4530(90)90067-J
G Cizza, K Pacak, R Kvetnansky, M Palkovits, D S Goldstein, L S Brady, K Fukuhara, E Bergamini, I J Kopin, M R Blackman, Decreased stress responsivity of central and peripheral catecholaminergic systems in aged 344/N Fischer rats. Journal of Clinical Investigation. ,vol. 95, pp. 1217- 1224 ,(1995) , 10.1172/JCI117771