Impact of clonal evolution on the biological diversity of Trypanosoma cruzi.

摘要: Trypanosoma cruzi, the agent of Chagas' disease, exhibits considerable biological variability. Moreover, it has been postulated that populations this protozoan are subdivided into natural clones, which can be separated from each other by levels evolutionary divergence. The authors have proposed long-term clonal evolution may a profound impact on cruzi diversity. In order to test hypothesis, 16 T. stocks representing 3 major genotypes parasite were analysed for 8 different in vitro parameters. overall results show strong statistical linkage between genetic and differences. This is agreement with working although notable variability observable among genotypes. propose must taken account any applied study dealing parasite.