A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance
作者： Jens C Brüning , M.Dodson Michael , Jonathon N Winnay , Tatsuya Hayashi , Dieter Hörsch
DOI: 10.1016/S1097-2765(00)80155-0
关键词: Insulin receptor 、 Metabolic syndrome 、 Skeletal muscle 、 Biology 、 Type 2 diabetes 、 Randle cycle 、 Internal medicine 、 Insulin 、 Glucose tolerance test 、 Insulin resistance 、 Endocrinology
摘要: Skeletal muscle insulin resistance is among the earliest detectable defects in humans with type 2 diabetes mellitus. To determine the contribution of muscle insulin resistance to the …
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