On a geometry-based approach to protein sequence alignment
作者： Milan Randić
DOI: 10.1007/S10910-007-9229-7
关键词: Sequence logo 、 Sequence alignment 、 Multiple sequence alignment 、 Structural alignment 、 Unit circle 、 Protein sequencing 、 Mathematics 、 Geometry 、 Homology modeling 、 Sequence (medicine) 、 Algorithm
摘要: We consider a novel numerical representation of proteins obtained by assigning to individual amino acids the polar coordinate on unit circle. As result one can represent protein sequence as one-dimensional sequence, entries which when subtracted facilitates search for alignment between pairs interest. The is sought shifting relative another several units left or right. approach illustrated two yeast having 174 and 171 acids.
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