作者: Kiyoshi Makiyama , Ryoji Hirai , Hiroumi Matsuzaki , Minoru Ikeda
DOI: 10.1016/J.JVOICE.2012.10.014
关键词: Human Papillomavirus DNA Test 、 Carcinoma 、 Oncology 、 Case-control study 、 Predictive value of tests 、 Pathology 、 Recurrent Respiratory Papillomatosis 、 Typing 、 Papilloma 、 Internal medicine 、 Medicine 、 HPV infection
摘要: Summary Objectives Human papilloma virus (HPV) infection is involved in both juvenile and adult laryngeal papilloma. We wished to determine which types of were clinically related HPV infection. hypothesized that multiple-site recurrent papillomas would have a strong relationship conducted the present study test this hypothesis. Methods Thirteen male patients with who underwent resection between August 2006 September 2009 studied. examined relationships whether tumor was solitary or multiple, presence absence recurrence after surgery, High-risk (HPV-DNA 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68) low-risk (6, 11, 42, 43, 44) tested by liquid-phase hybridization method. In addition, typing performed for positive types. Twenty carcinoma leukoplakia enrolled as control group. Results group, all negative high-risk 69.2% HPV. Typing seven showed one patient HPV-11, whereas remaining six HPV-6. All papillomatosis (RLP) had RLP. Tumor samples from repeat operations tested. not detected Conclusions The RLP strong, cases showing recurrence. tissue resected at time surgery