First total synthesis of paecilodepsipeptide A
作者： Ming Jun Yang , Jing Wu , Zhong Duo Yang , Ying Mei Zhang
DOI: 10.1016/J.CCLET.2009.01.032
关键词: Stereochemistry 、 Total synthesis 、 Peptide chemistry 、 Chemistry
摘要: Abstract The first total synthesis of paecilodepsipeptide A is reported. convergent, flexible strategy employing peptide chemistry and culminating in macrolactamisation described. previously reported structure compound confirmed.
elsevier.com
sci-hub.se 参考文章(13)
Gerhard Lang, John W. Blunt, Nicholas J. Cummings, Anthony L. J. Cole, Murray H. G. Munro, Paecilosetin, a new bioactive fungal metabolite from a New Zealand isolate of Paecilomyces farinosus. Journal of Natural Products. ,vol. 68, pp. 810- 811 ,(2005) , 10.1021/NP0500979
Gerhard Lang, Maya I. Mitova, Gill Ellis, Sonia van der Sar, Richard K. Phipps, John W. Blunt, Nicholas J. Cummings, Anthony L. J. Cole, Murray H. G. Munro, Bioactivity profiling using HPLC/microtiter-plate analysis: application to a New Zealand marine alga-derived fungus, Gliocladium sp. Journal of Natural Products. ,vol. 69, pp. 621- 624 ,(2006) , 10.1021/NP0504917
Louis A. Carpino, Ayman El-Faham, Charles A. Minor, Fernando Albericio, Advantageous applications of azabenzotriazole (triazolopyridine)-based coupling reagents to solid-phase peptide synthesis Journal of the Chemical Society, Chemical Communications. pp. 201- 203 ,(1994) , 10.1039/C39940000201
Masahiko Isaka, Somporn Palasarn, Sanisa Lapanun, Kanlayanee Sriklung, Paecilodepsipeptide A, an Antimalarial and Antitumor Cyclohexadepsipeptide from the Insect Pathogenic Fungus Paecilomyces cinnamomeus BCC 9616 Journal of Natural Products. ,vol. 70, pp. 675- 678 ,(2007) , 10.1021/NP060602H
Yuzuru Mikami, Katsukiyo Yazawa, Kazutaka Fukushima, Tadashi Arai, Shun-ichi Udagawa, Robert A. Samson, Paecilotoxin production in clinical or terrestrial isolates of Paecilomyces lilacinus strains. Mycopathologia. ,vol. 108, pp. 195- 199 ,(1989) , 10.1007/BF00436225
ANDREAS FREDENHAGEN, PAUL HUG, HANSPETER SAUTER, HEINRICH H. PETER, Paeciloquinones A, B, C, D, E and F:New Potent Inhibitors of Protein Tyrosine Kinase Produced by Paecilomyces carneus II.Characterization and Structure Determination The Journal of Antibiotics. ,vol. 48, pp. 199- 204 ,(1995) , 10.7164/ANTIBIOTICS.48.199
Rieko van Heerbeek, Paul C. J. Kamer, Piet N. M. W. van Leeuwen, Joost N. H. Reek, Synthesis of carbosilane dendritic wedges and their use for the construction of dendritic receptors Organic and Biomolecular Chemistry. ,vol. 4, pp. 211- 223 ,(2006) , 10.1039/B514583J
Clavicipitalean Fungi: evolutionary biology, chemistry, biocontrol and cultural impacts. Clavicipitalean Fungi: evolutionary biology, chemistry, biocontrol and cultural impacts.. ,(2003) , 10.1201/9780203912706
Haruhisa Kikuchi, Yasuhiro Miyagawa, Yuko Sahashi, Satoshi Inatomi, Asami Haganuma, Norimichi Nakahata, Yoshiteru Oshima, Novel trichothecanes, paecilomycine A, B, and C, isolated from entomopathogenic fungus, Paecilomyces tenuipes Tetrahedron Letters. ,vol. 45, pp. 6225- 6228 ,(2004) , 10.1016/J.TETLET.2004.06.107
KAZUTAKA FUKUSHIMA, TADASHI ARAI, YUJI MORI, MAKOTO TSUBOI, MAKOTO SUZUKI, Studies on peptide antibiotics, leucinostatins. II: The structures of leucinostatins A and B The Journal of Antibiotics. ,vol. 36, pp. 1613- 1630 ,(1983) , 10.7164/ANTIBIOTICS.36.1613