Novel trichothecanes, paecilomycine A, B, and C, isolated from entomopathogenic fungus, Paecilomyces tenuipes

作者: Haruhisa Kikuchi , Yasuhiro Miyagawa , Yuko Sahashi , Satoshi Inatomi , Asami Haganuma

DOI: 10.1016/J.TETLET.2004.06.107

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摘要: Paecilomycine A (1), B (2), and C (3) were isolated from cultivated fruiting bodies of Paecilomyces tenuipes (Isaria japonica), which is a popular entomopathogenic fungus used in folk medicine health foods China, Korea, Japan. The structures 1–3 deduced their spectroscopic data absolute configurations elucidated by preparing MPA esters. Compound 1 showed activity the neurotrophic factor biosynthesis glial cells.

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