Expression of 1A6 gene and its correlation with intestinal gastric carcinoma

摘要: AIM: To investigate the expression of 1A6 gene in lesions during development intestinal gastric carcinoma. METHODS: One hundred and thirty-six cases metaplasia (IM) from surgical resections biopsy were classified by mucous staining. Expression all was detected using immunohistochemical S-P method. RESULTS: The positive rates normal superficial gastritis (SG), severe atrophic (SAG), type I, II, III IM, dysplasia (Dys) carcinoma (IGC) 12.2%, 16.7%, 7.1%, 22.6%, 47.8%, 46.9% 60.8%, respectively. A significant difference among IM SG, SAG, I II found (P < 0.01), between Dys, IGC being not significant. CONCLUSION: As a new tumor-related gene, may be an effective parameter to predict malignant transformation precancerous lesion carcinoma.