Oxysterols and mesenchymal stem cell biology.
作者： Débora Levy , Thatiana Correa de Melo , Jorge L.M. Ruiz , Sérgio P. Bydlowski
DOI: 10.1016/J.CHEMPHYSLIP.2017.06.009
关键词: Mesenchymal stem cell 、 Cell biology 、 Hedgehog signaling pathway 、 Oxysterol 、 Chemistry 、 Cellular differentiation 、 Mesenchymal stem cell differentiation 、 Cell signaling 、 Cell type 、 Endothelial stem cell
摘要: Abstract Oxysterols are oxidized products of cholesterol that play several roles in various pathophysiological processes, including the control lipid metabolism, immunological and cytotoxicity. Mesenchymal stem cells multipotent with properties self-renewal ability to differentiate into other cell types, osteoblasts adipocytes. Here, we review literature regarding effects oxysterols on mesenchymal differentiation main signaling pathways involved this process.
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